Ibuprofen belongs to a class of drugs called nonsteroidal anti-inflammatory drugs, generally referred to as “NSAIDs”. This is the generic name for brands such as Advil, Motrin and others.

These drugs are used for the management of mild to moderate pain, fever, and inflammation. They work by reducing the levels of prostaglandins, chemicals that are responsible for pain, fever, and inflammation.

Ibuprofen was patented in 1961 as a result of research in the 1950s and 1960s to find a safer alternative to aspirin. In the early 1980s, it became the first NSAID alternative to aspirin to become available over the counter.

NSAIDs reduce the flow of blood to the kidneys, which may impair their function. The impairment is most likely to occur in patients with preexisting impairment of kidney function or congestive heart failure, and use of NSAIDs in these patients should be done cautiously.

NSAIDs also reduce the ability of blood to clot and therefore are likely to increase bleeding after an injury.

NSAIDs increase the risk of potentially fatal, stomach and intestinal adverse reactions (for example, bleeding, ulcers, and perforation of the stomach or intestines). Sometimes, stomach ulceration and intestinal bleeding can occur without any abdominal pain. Black tarry stools, weakness, and dizziness upon standing may be the only signs of the bleeding.

NSAIDs, except low dose aspirin, may increase the risk of potentially fatal heart attacks, stroke, and related conditions. This risk may increase with duration of use and in patients who have underlying risk factors for heart and blood vessel disease. Therefore, NSAIDs should not be used for the treatment of pain resulting from coronary artery bypass graft (CABG) surgery.

Higher doses of Ibuprofen are available by prescription. You could also just take more pills at once (but you shouldn’t do that).

As you can buy Ibuprofen over the counter just about anywhere – airports, convenience stores, discount stores, drug stores, grocery stores, hotel shops, etc – you can take care of what ails you almost whenever you need.

My own experience is that it just depends on what is bothering me, but it is almost always a headache. I like to tell people my brain continues to grow, but at this point, I don’t think that anyone believes me.

The instructions typically say to take 1 tablet (200mg) every 4-6 hours, not to exceed 6 (1200mg) in a 24 hour period, but I usually need 2 (400mg). In extreme cases, I may need 3 (600mg) or even 4 (800mg), because knocking it out quickly is often better than hanging on without much effect, but ultimately you really need to take care not to exceed the amount you take over the course of a day.

2 Replies to “Ibuprofen”

  1. I have been suffering from GOUT for some time now (since 2005). The last six months the only remedy to relieve the pain and the inflamation of the joints at my big toe and knee was Ibuprofen 600. I have been taken these pills every day for about 4 months now. I have had no side effects or stomach problems. Luckily I found (I think) a cure for my illness last week. I have not been drinking milk for about 20 years now. Last week by chance I started to drink warm milk before I go to bed. After a couple of days I noticed that I was not getting the pain I usually get when the Ibuprofen wears off. Now is a week I have been drinking milk (powder milk) and not drinking the Ibuprofen and not having any pain. I hope this information can help someone with the same symptons as I.

  2. When I really need pain relief, I take 600 mg of ibuprofen at a shot. 200 just doesn’t cut it. I have found that the sooner you take it, the sooner you get releif. The next day after my chemo treatment, I get a Neulasta shot that gives me a lot of body pain about six hours later. I have found that taking 600 mg every four hours about six hour BEFORE the shot really reduces the pain.

    My father was on 2400 mg for a while for his back pain. The only problem with ibuprofen is, it is tough on your stomach. Try to have something to eat the same time you take it. And I would recommend 600 mg at a crach.

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